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Alpha-GPC
TL;DR
Alpha-glycerylphosphorylcholine (Alpha-GPC) is the most bioavailable choline source for the brain, crossing the BBB to directly increase acetylcholine synthesis. It also stimulates growth hormone release.
Overview
Alpha-glycerylphosphorylcholine (Alpha-GPC) is the most bioavailable choline source for the brain, crossing the BBB to directly increase acetylcholine synthesis. It also stimulates growth hormone release. Used clinically in Europe for cognitive decline (as Gliatilin/Delecit).
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products in our database contain Alpha-GPC
Source · MoodStack database
Benefits
- Acetylcholine enhancement
- Cognitive enhancement
- Growth hormone release
- Power output
- Neuroprotection
Dose guide
Common dose
300-1200 mg daily
Typical range
300–1200 mg
Based on 13 products in our database.
Products with Alpha-GPC
Transparent Labs BULK Pre-Workout
Gorilla Mode Lightning
Transparent Labs Stim-Free Pre-Workout
Transparent Labs BULK Black Pre-Workout
Gorilla Mind Nootropic
Gorilla Mind Energy Drink
Gorilla Mode Base Pre-Workout
Gorilla Mind Energy Shot
Gorilla Mind Respawn
Gorilla Mind Smooth
Interactions
synergistic. Alpha-GPC boosts acetylcholine for memory and focus while caffeine blocks adenosine for alertness; complementary cognitive enhancement via different neurotransmitter systems
synergistic. Racetams increase acetylcholine receptor sensitivity and utilization; Alpha-GPC ensures adequate acetylcholine supply to meet increased demand, preventing headaches
enhances. Alpha-GPC increases acetylcholine production while AChE inhibitors prevent breakdown; combined may cause cholinergic excess (nausea, salivation, muscle cramps)
synergistic. Alpha-GPC provides acetylcholine fuel for cognitive processing while phosphatidylserine maintains neuronal membrane fluidity for efficient neurotransmission
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Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.