alkaloid
Huperzine A
TL;DR
Huperzine A is a sesquiterpene alkaloid isolated from Chinese club moss (Huperzia serrata). It is a highly selective and reversible acetylcholinesterase (AChE) inhibitor with superior blood-brain barrier penetration compared to pharmaceutical AChE inhibitors.
Overview
Huperzine A is a sesquiterpene alkaloid isolated from Chinese club moss (Huperzia serrata). It is a highly selective and reversible acetylcholinesterase (AChE) inhibitor with superior blood-brain barrier penetration compared to pharmaceutical AChE inhibitors. Used for cognitive enhancement and as a neuroprotective agent.
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products in our database contain Huperzine A
Source · MoodStack database
Compound forms
Huperzine A comes in several molecular forms. Each absorbs and acts differently.
Huperzine A (H. serrata) extract
Huperzine A (from Huperzia serrata)
Bioavailability
70%
Typical dose
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Benefits
- Cognitive enhancement
- Neuroprotection
- NMDA receptor modulation
- Learning enhancement
Dose guide
Common dose
50-200 mcg 1-2x daily (cycle: 2-4 weeks on, 1 week off)
Typical range
50–400 mcg
Based on 9 products in our database.
Products with Huperzine A
Gorilla Mind Nootropic
Gorilla Mind Energy Drink
Gorilla Mode Base Pre-Workout
Gorilla Mind Energy Shot
Gorilla Mind Respawn
Gorilla Mode Pre-Workout
Gorilla Mind Rush
Gorilla Mind Smooth
Thavage Pre-Workout
Interactions
synergistic. Huperzine A inhibits acetylcholinesterase (preserving acetylcholine) while Alpha-GPC increases acetylcholine production; synergistic cholinergic enhancement
enhances. Huperzine A is itself an AChE inhibitor; combining with pharmaceutical AChE inhibitors (donepezil, rivastigmine) may cause severe cholinergic crisis
competes. Huperzine A increases acetylcholine while anticholinergics (diphenhydramine, oxybutynin) block acetylcholine receptors; opposing mechanisms reduce effectiveness of both
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Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.