amino_acid

Valine

TL;DR

L-Valine is an essential branched-chain amino acid (BCAA) that works alongside leucine and isoleucine in muscle metabolism. While less anabolic than leucine individually, valine is critical for maintaining nitrogen balance, preventing muscle breakdown during exercise, and serving as glucogenic fuel.

Overview

L-Valine is an essential branched-chain amino acid (BCAA) that works alongside leucine and isoleucine in muscle metabolism. While less anabolic than leucine individually, valine is critical for maintaining nitrogen balance, preventing muscle breakdown during exercise, and serving as glucogenic fuel.

12 / 565

products in our database contain Valine

Source · MoodStack database

Compound forms

Valine comes in several molecular forms. Each absorbs and acts differently.

L-Valine

2-amino-3-methylbutanoic acid

Bioavailability

98%

Typical dose

2–10 g

Benefits

  • Muscle maintenance
  • Anti-catabolic
  • Central fatigue reduction
  • Glycogen sparing

Dose guide

Common dose

1-5 g daily (typically as part of BCAA blend in 2:1:1 ratio)

Typical range

10005000 mg

Based on 12 products in our database.

Products with Valine

Interactions

synergistic. Valine provides BCAA energy substrate during exercise while leucine triggers mTOR; together they reduce exercise-induced BCAA oxidation and central fatigue

competes. Valine competes with tryptophan for BBB transport via LAT1; high valine reduces brain serotonin (anti-fatigue during exercise but may worsen mood at rest)

competes. BCAAs including valine compete with L-DOPA for LAT1 transport across the BBB; high BCAA intake may reduce levodopa effectiveness

Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.

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