amino_acid

Arginine

TL;DR

L-Arginine is a semi-essential amino acid and the primary precursor to nitric oxide (NO) via nitric oxide synthase. It plays critical roles in vasodilation, immune function, growth hormone secretion, and wound healing.

Overview

L-Arginine is a semi-essential amino acid and the primary precursor to nitric oxide (NO) via nitric oxide synthase. It plays critical roles in vasodilation, immune function, growth hormone secretion, and wound healing. Widely used for cardiovascular support and exercise performance.

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products in our database contain Arginine

Source · MoodStack database

Compound forms

Arginine comes in several molecular forms. Each absorbs and acts differently.

Arginine Alpha-Ketoglutarate (AAKG)

(2S)-2-amino-5-guanidinopentanoic acid + 2-oxopentanedioate

Bioavailability

65%

Typical dose

3–10 g

L-Arginine

(2S)-2-amino-5-guanidinopentanoic acid

Bioavailability

70%

Typical dose

3–30 g

Benefits

  • Nitric oxide production
  • Cardiovascular health
  • Exercise performance
  • Growth hormone release
  • Wound healing

Dose guide

Common dose

3-6 g daily

Typical range

30006000 mg

Based on 6 products in our database.

Products with Arginine

Interactions

synergistic. Citrulline converts to arginine in the kidneys but with better oral bioavailability; citrulline actually raises plasma arginine more effectively than oral arginine itself

enhances. Arginine increases NO production while PDE5 inhibitors prevent breakdown of NO-mediated cGMP; combined may cause excessive vasodilation and dangerous hypotension

competes. Arginine and lysine compete for the same CAT1 transporter; high arginine may promote herpes simplex replication while lysine inhibits it

enhances. Arginine lowers blood pressure via nitric oxide-mediated vasodilation; additive effects with antihypertensive medications

Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.

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