Supplements to support muscle growth and strength.
Top picks for Muscle Gain supplements based on scientific evidence and product analysis.
Fat-soluble secosteroid vitamin synthesized in skin upon UVB exposure. Functions as a hormone affecting calcium homeostasis and bone health.
Benefits: Essential for calcium absorption and bone health, Supports immune system function, May reduce risk of autoimmune diseases, Supports muscle function, May improve mood and reduce depression risk
Found in 115 products
Essential trace mineral critical for immune function, wound healing, protein synthesis, and DNA synthesis.
Benefits: Essential for immune system function, Supports wound healing, Important for protein and DNA synthesis, Supports reproductive health, May reduce duration of common cold
Found in 89 products
Essential mineral involved in over 300 enzymatic reactions including energy production, protein synthesis, muscle/nerve function, and blood pressure regulation.
Benefits: Supports muscle and nerve function, Essential for energy production, May improve sleep quality, Supports bone health, May reduce anxiety and stress, Important for blood pressure regulation
Found in 82 products
L-Citrulline is a non-essential amino acid named after watermelon (Citrullus lanatus). It is converted to L-arginine in the kidneys, making it a more efficient NO booster than arginine itself (arginine undergoes significant first-pass metabolism). One of the most validated pre-workout ingredients for blood flow and endurance.
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Found in 25 products
Adaptogenic herb (Withania somnifera) used for thousands of years in Ayurvedic medicine.
Benefits: Reduces cortisol and stress levels, May improve anxiety symptoms, May enhance testosterone in men, Supports energy and endurance, May improve sleep quality, May support thyroid function
Found in 21 products
Beta-alanine is a non-essential amino acid and the rate-limiting precursor to carnosine synthesis in skeletal muscle. Carnosine acts as an intracellular pH buffer during high-intensity exercise. It is one of the most well-researched sports nutrition supplements with strong evidence for exercise performance improvement.
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Found in 21 products
L-Carnitine is a conditionally essential amino acid derivative synthesized from lysine and methionine. It is critical for transporting long-chain fatty acids into mitochondria for beta-oxidation (energy production). It also removes toxic acyl-CoA metabolites and has neuroprotective properties. ALCAR (acetyl-L-carnitine) crosses the blood-brain barrier.
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Found in 17 products
L-Leucine is the most anabolic of the three BCAAs and the primary activator of the mTOR (mammalian target of rapamycin) pathway for muscle protein synthesis. The "leucine threshold" concept (2.5-3g per meal) is central to modern sports nutrition for optimizing muscle growth and preventing sarcopenia.
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Found in 13 products
Naturally occurring compound stored primarily in muscles as phosphocreatine. Serves as rapid energy reserve for high-intensity activities.
Benefits: Increases muscle strength and power, Improves high-intensity exercise performance, May support cognitive function, Supports muscle recovery, May increase lean muscle mass
Found in 11 products
Branched-chain amino acids (leucine, isoleucine, valine) promote muscle protein synthesis, reduce muscle soreness, and enhance exercise performance. They support recovery by minimizing muscle breakdown during intense workouts. Found in protein-rich foods and supplements.
Benefits: Enhances muscle protein synthesis and reduces muscle breakdown
Found in 10 products
L-Arginine is a semi-essential amino acid and the primary precursor to nitric oxide (NO) via nitric oxide synthase. It plays critical roles in vasodilation, immune function, growth hormone secretion, and wound healing. Widely used for cardiovascular support and exercise performance.
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Found in 6 products
Casein is the predominant protein in milk (80%), known for its slow digestion and sustained amino acid release over 6-8 hours. It forms a gel (clot) in the stomach, providing a time-released delivery of amino acids. Micellar casein is the least processed form; casein hydrolysate is pre-digested for faster absorption.
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Found in 5 products
Eurycoma longifolia (Tongkat Ali/Long Jack) is a Southeast Asian herb with strong clinical evidence for testosterone optimization, male fertility, and adaptogenic stress relief. Active compounds (eurycomanone, quassinoids) reduce SHBG, increase free testosterone, and lower cortisol.
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Found in 3 products
Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.
