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DIM
TL;DR
Diindolylmethane (DIM) is a compound formed from indole-3-carbinol (I3C) during digestion of cruciferous vegetables. It modulates estrogen metabolism, shifting it toward protective 2-hydroxyestrone metabolites instead of harmful 16-alpha-hydroxyestrone and 4-hydroxyestrone.
Overview
Diindolylmethane (DIM) is a compound formed from indole-3-carbinol (I3C) during digestion of cruciferous vegetables. It modulates estrogen metabolism, shifting it toward protective 2-hydroxyestrone metabolites instead of harmful 16-alpha-hydroxyestrone and 4-hydroxyestrone.
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products in our database contain DIM
Source · MoodStack database
Benefits
- Estrogen metabolism optimization
- Hormonal balance
- Cancer prevention
- Anti-androgenic acne
Dose guide
Common dose
100-300 mg daily with food
Typical range
100–300 mg
Based on 5 products in our database.
Products with DIM
Interactions
synergistic. DIM shifts estrogen toward protective 2-OHE1 metabolites while zinc supports aromatase regulation and testosterone synthesis; complementary hormonal optimization
synergistic. DIM promotes phase I estrogen hydroxylation while calcium D-glucarate supports phase II glucuronidation for estrogen excretion; complete estrogen clearance pathway
enhances. DIM alters estrogen metabolite ratios and may reduce efficacy of estrogen-based therapies by shifting metabolism toward less potent metabolites
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Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.