Supplements supporting testosterone, estrogen balance, thyroid, and overall hormonal optimization
Top picks for Hormonal Health supplements based on scientific evidence and product analysis.
Fat-soluble secosteroid vitamin synthesized in skin upon UVB exposure. Functions as a hormone affecting calcium homeostasis and bone health.
Benefits: Essential for calcium absorption and bone health, Supports immune system function, May reduce risk of autoimmune diseases, Supports muscle function, May improve mood and reduce depression risk
Found in 115 products
Essential trace mineral critical for immune function, wound healing, protein synthesis, and DNA synthesis.
Benefits: Essential for immune system function, Supports wound healing, Important for protein and DNA synthesis, Supports reproductive health, May reduce duration of common cold
Found in 89 products
Essential mineral involved in over 300 enzymatic reactions including energy production, protein synthesis, muscle/nerve function, and blood pressure regulation.
Benefits: Supports muscle and nerve function, Essential for energy production, May improve sleep quality, Supports bone health, May reduce anxiety and stress, Important for blood pressure regulation
Found in 82 products
Water-soluble vitamin with pyridoxal 5-phosphate (P5P) being the active coenzyme. Involved in over 100 enzymatic reactions.
Benefits: Essential for protein metabolism, Supports neurotransmitter synthesis, Important for hemoglobin production, May help reduce homocysteine levels, Supports immune function
Found in 79 products
Adaptogenic herb (Withania somnifera) used for thousands of years in Ayurvedic medicine.
Benefits: Reduces cortisol and stress levels, May improve anxiety symptoms, May enhance testosterone in men, Supports energy and endurance, May improve sleep quality, May support thyroid function
Found in 21 products
Boron is an essential trace mineral involved in bone metabolism, hormone regulation, and cognitive function. It influences the metabolism of calcium, magnesium, and vitamin D, and modulates steroid hormone levels including testosterone and estrogen. Often overlooked but critical for skeletal and hormonal health.
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Found in 12 products
Diindolylmethane (DIM) is a compound formed from indole-3-carbinol (I3C) during digestion of cruciferous vegetables. It modulates estrogen metabolism, shifting it toward protective 2-hydroxyestrone metabolites instead of harmful 16-alpha-hydroxyestrone and 4-hydroxyestrone.
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Found in 5 products
Maca (Lepidium meyenii) is a Peruvian cruciferous root vegetable grown at 4,000+ meters altitude. Different color varieties (red, black, yellow) have distinct properties. It does not directly alter hormones but modulates the hypothalamic-pituitary axis. Clinically validated for libido, energy, fertility, and mood.
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Found in 3 products
Eurycoma longifolia (Tongkat Ali/Long Jack) is a Southeast Asian herb with strong clinical evidence for testosterone optimization, male fertility, and adaptogenic stress relief. Active compounds (eurycomanone, quassinoids) reduce SHBG, increase free testosterone, and lower cortisol.
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Found in 3 products
Saw palmetto (Serenoa repens) is a palm berry extract used primarily for benign prostatic hyperplasia (BPH) and male hormonal health. It inhibits 5-alpha reductase (blocking DHT conversion) and has anti-inflammatory effects on prostate tissue. One of the most popular men's health supplements worldwide.
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Found in 3 products
Shilajit is a mineral-rich resinous substance found in Himalayan rock formations. It contains fulvic acid, dibenzo-alpha-pyrones, and 85+ minerals. Ayurvedic rasayana (rejuvenator) with clinical evidence for testosterone, mitochondrial function, and CoQ10 enhancement.
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Found in 2 products
For testosterone support, the evidence-based stack is Vitamin D (3000-5000 IU) + Zinc (30mg) + Magnesium (400mg) — often called the ZMA+ stack. Add Ashwagandha (KSM-66, 600mg) to control cortisol.
For enhanced optimization, Tongkat Ali (400mg) pairs well with Ashwagandha — they work through different mechanisms.
For women: DIM (100-200mg) supports healthy estrogen metabolism, while Maca (1500-3000mg) helps with menopausal symptoms and libido.
Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.
