mushroom
Lion’s Mane
TL;DR
Lion's Mane (Hericium erinaceus) stimulates Nerve Growth Factor (NGF) production through hericenones and erinacines. The only known natural substance that significantly upregulates NGF synthesis in the brain.
Overview
Lion's Mane (Hericium erinaceus) stimulates Nerve Growth Factor (NGF) production through hericenones and erinacines. The only known natural substance that significantly upregulates NGF synthesis in the brain. Research supports cognitive enhancement, nerve regeneration, and neuroprotection.
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products in our database contain Lion’s Mane
Source · MoodStack database
Compound forms
Lion’s Mane comes in several molecular forms. Each absorbs and acts differently.
Lion’s Mane
Hericium erinaceus
Bioavailability
30%
Typical dose
1000–3000 mg
Benefits
- NGF stimulation
- Cognitive enhancement
- Nerve regeneration
- Depression and anxiety
- Gut health
- Immune modulation
Dose guide
Common dose
500-3000 mg extract daily
Typical range
500–3000 mg
Based on 4 products in our database.
Products with Lion’s Mane
Interactions
synergistic. Lion’s Mane promotes NGF/BDNF-mediated neurogenesis while ashwagandha reduces cortisol-induced neuronal damage; comprehensive neuroprotective stack
synergistic. Niacin supports NAD+ for neuronal energy metabolism while Lion’s Mane enhances nerve growth factor; complementary neurological support
enhances. Lion’s Mane may have mild antiplatelet aggregation activity via hericenone B
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Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.