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  3. Lion’s Mane vs Theanine

Lion’s Mane vs Theanine

TL;DR

Quick comparison: Lion’s Mane and Theanine have 1 overlapping categories and appear together in 2 products.

  • •Choose Lion’s Mane if: Lion's Mane (Hericium erinaceus) stimulates Nerve Growth Factor (NGF) production...
  • •Choose Theanine if: L-Theanine promotes relaxation without drowsiness, reduces stress, and improves ...
  • •Take both if: You want comprehensive coverage across 1 shared categories.
564 products
analyzed in our comprehensive supplement database
Source: MoodStack Database (2026)

Side-by-Side Comparison

FeatureLion’s ManeTheanine
Typemushroomamino_acid
Common Dosage500-3000 mg extract daily200 mg
Best BioavailabilityLion’s Mane (30%)L-Theanine (90%)
Categories14
Available Products00

Lion’s Mane

Typemushroom
Common Dosage500-3000 mg extract daily
Best BioavailabilityLion’s Mane (30%)
Categories1
Available Products0

Theanine

Typeamino_acid
Common Dosage200 mg
Best BioavailabilityL-Theanine (90%)
Categories4
Available Products0

Can You Take Both?

Yes, Lion’s Mane and Theanine can typically be taken together. In fact, we found 2 products in our database that contain both supplements, suggesting they complement each other well.

Both supplements share 1 common category, indicating they may work synergistically for similar health goals.

Key Differences

Lion’s Mane

Lion's Mane (Hericium erinaceus) stimulates Nerve Growth Factor (NGF) production through hericenones and erinacines. The only known natural substance that significantly upregulates NGF synthesis in the brain. Research supports cognitive enhancement, nerve regeneration, and neuroprotection.

Categories:

Focus & Cognition

Common Forms:

  • • Lion’s Mane (30% bioavailability)

Theanine

L-Theanine promotes relaxation without drowsiness, reduces stress, and improves focus when paired with caffeine. It supports sleep quality and enhances alpha brain wave activity. Found in green tea and supplements.

Categories:

Fat LossSleepFocus & CognitionStress & Mood

Common Forms:

  • • L-Theanine (90% bioavailability)

Shared Categories

Both Lion’s Mane and Theanine are used for these health goals:

🧠Focus & Cognition

Products Containing Both Lion’s Mane and Theanine

We found 2 products that combine both supplements:

Gorilla Mind Nootropic

Gorilla Mind Nootropic

Gorilla Mind

$49.99Score: 88/100
Gorilla Mind Smooth

Gorilla Mind Smooth

Gorilla Mind

$49.99Score: 85/100

Frequently Asked Questions

What is the difference between Lion’s Mane and Theanine?

Lion’s Mane and Theanine are both important supplements with distinct properties. Lion’s Mane Lion's Mane (Hericium erinaceus) stimulates Nerve Growth Factor (NGF) production through hericenones and erinacines. The only known natural substance that significantly upregulates NGF synthesis in the brain. Research supports cognitive enhancement, nerve regeneration, and neuroprotection., while Theanine L-Theanine promotes relaxation without drowsiness, reduces stress, and improves focus when paired with caffeine. It supports sleep quality and enhances alpha brain wave activity. Found in green tea and supplements..

Can I take Lion’s Mane and Theanine together?

Based on our analysis of 2 products that contain both, yes, Lion’s Mane and Theanine can typically be taken together. However, always consult with a healthcare provider before combining supplements.

Which is more popular: Lion’s Mane or Theanine?

In our database of 564 products, Lion’s Mane appears in 4 products, while Theanine appears in 26 products.

Related Comparisons & Products

What is Lion’s Mane?What is Theanine?Vitamin B6 vs TheanineTheanine vs ValerianGinseng vs TheanineGorilla Mind Nootropic (contains both)Gorilla Mind Smooth (contains both)

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.