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  3. Lysine vs Phenylalanine

Lysine vs Phenylalanine

TL;DR

Quick comparison: Lysine and Phenylalanine have 0 overlapping categories and appear together in 3 products.

  • •Choose Lysine if: L-Lysine is an essential amino acid critical for collagen synthesis, calcium abs...
  • •Choose Phenylalanine if: L-Phenylalanine supports mood by aiding dopamine and norepinephrine production, ...
  • •Take both if: You want comprehensive coverage across 0 shared categories.
564 products
analyzed in our comprehensive supplement database
Source: MoodStack Database (2026)

Side-by-Side Comparison

FeatureLysinePhenylalanine
Typeamino_acidamino_acid
Common Dosage500-3000 mg daily500 mg
Best BioavailabilityL-Lysine (95%)L-Phenylalanine (90%)
Categories00
Available Products00

Lysine

Typeamino_acid
Common Dosage500-3000 mg daily
Best BioavailabilityL-Lysine (95%)
Categories0
Available Products0

Phenylalanine

Typeamino_acid
Common Dosage500 mg
Best BioavailabilityL-Phenylalanine (90%)
Categories0
Available Products0

Can You Take Both?

Yes, Lysine and Phenylalanine can typically be taken together. In fact, we found 3 products in our database that contain both supplements, suggesting they complement each other well.

Key Differences

Lysine

L-Lysine is an essential amino acid critical for collagen synthesis, calcium absorption, carnitine production, and immune function. Best known for antiviral activity against herpes simplex virus by antagonizing arginine.

Categories:

Common Forms:

  • • L-Lysine (95% bioavailability)

Phenylalanine

L-Phenylalanine supports mood by aiding dopamine and norepinephrine production, enhancing focus and reducing depression. It may help manage chronic pain. Found in protein-rich foods like eggs, soy, and supplements.

Categories:

Common Forms:

  • • L-Phenylalanine (90% bioavailability)
  • • N-Acetyl-L-Phenylalanine (70% bioavailability)
  • • Phenylalanine ethyl ester (60% bioavailability)

Products Containing Both Lysine and Phenylalanine

We found 3 products that combine both supplements:

Gorilla Mode EAAs

Gorilla Mode EAAs

Gorilla Mind

$39.99Score: 88/100
PLAY! - IntraWorkout

PLAY! - IntraWorkout

Raptor Nutrition

$39.99Score: 84/100
EAA Essential Amino Acids 300 g

EAA Essential Amino Acids 300 g

Prozis

$1699Score: 49/100

Frequently Asked Questions

What is the difference between Lysine and Phenylalanine?

Lysine and Phenylalanine are both important supplements with distinct properties. Lysine L-Lysine is an essential amino acid critical for collagen synthesis, calcium absorption, carnitine production, and immune function. Best known for antiviral activity against herpes simplex virus by antagonizing arginine., while Phenylalanine L-Phenylalanine supports mood by aiding dopamine and norepinephrine production, enhancing focus and reducing depression. It may help manage chronic pain. Found in protein-rich foods like eggs, soy, and supplements..

Can I take Lysine and Phenylalanine together?

Based on our analysis of 3 products that contain both, yes, Lysine and Phenylalanine can typically be taken together. However, always consult with a healthcare provider before combining supplements.

Which is more popular: Lysine or Phenylalanine?

In our database of 564 products, Lysine appears in 4 products, while Phenylalanine appears in 5 products.

Related Comparisons & Products

What is Lysine?What is Phenylalanine?Valine vs LysineValine vs PhenylalanineLysine vs IsoleucineGorilla Mode EAAs (contains both)PLAY! - IntraWorkout (contains both)EAA Essential Amino Acids 300 g (contains both)

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.