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Apigenin
TL;DR
Apigenin is a flavonoid abundant in chamomile, parsley, and celery. It binds to GABA-A benzodiazepine receptors for anxiolytic effects, inhibits CD38 to increase NAD+, and has senolytic properties.
Overview
Apigenin is a flavonoid abundant in chamomile, parsley, and celery. It binds to GABA-A benzodiazepine receptors for anxiolytic effects, inhibits CD38 to increase NAD+, and has senolytic properties. One of Dr. Andrew Huberman's most-recommended sleep and longevity compounds.
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products in our database contain Apigenin
Source · MoodStack database
Benefits
- Sleep and anxiety
- NAD+ preservation
- Senolytic
- Anti-cancer
- Testosterone support
Dose guide
Common dose
50-500 mg daily (50mg for sleep; higher for NAD+ effects)
Typical range
50–500 mg
Based on 1 products in our database.
Products with Apigenin
Interactions
synergistic. Apigenin binds benzodiazepine sites on GABA-A receptors while magnesium modulates NMDA receptors; complementary calming pathways for sleep
synergistic. Both promote relaxation without sedation via different mechanisms: apigenin via GABA-A, L-theanine via alpha wave promotion and glutamate modulation
competes. Apigenin inhibits platelet aggregation and may have mild anticoagulant properties; could potentiate blood-thinning medications
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Medical disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.