General health boosters for energy and well‑being.
Top picks for Vitality supplements based on scientific evidence and product analysis.
Fat-soluble secosteroid vitamin synthesized in skin upon UVB exposure. Functions as a hormone affecting calcium homeostasis and bone health.
Benefits: Essential for calcium absorption and bone health, Supports immune system function, May reduce risk of autoimmune diseases, Supports muscle function, May improve mood and reduce depression risk
Found in 115 products
Water-soluble vitamin (cobalamin) containing cobalt, essential for DNA synthesis, neurological function, and red blood cell formation.
Benefits: Essential for nerve function and myelin synthesis, Required for red blood cell formation, Important for DNA synthesis, Supports energy metabolism, May improve mood and cognitive function
Found in 90 products
Essential mineral involved in over 300 enzymatic reactions including energy production, protein synthesis, muscle/nerve function, and blood pressure regulation.
Benefits: Supports muscle and nerve function, Essential for energy production, May improve sleep quality, Supports bone health, May reduce anxiety and stress, Important for blood pressure regulation
Found in 82 products
Water-soluble vitamin with pyridoxal 5-phosphate (P5P) being the active coenzyme. Involved in over 100 enzymatic reactions.
Benefits: Essential for protein metabolism, Supports neurotransmitter synthesis, Important for hemoglobin production, May help reduce homocysteine levels, Supports immune function
Found in 79 products
Essential mineral critical for oxygen transport (hemoglobin), energy production, and cellular function. Most common nutritional deficiency worldwide.
Benefits: Essential for oxygen transport in blood, Supports energy production, Important for immune function, Necessary for cognitive function, Required for hemoglobin synthesis
Found in 33 products
Adaptogenic herb (Withania somnifera) used for thousands of years in Ayurvedic medicine.
Benefits: Reduces cortisol and stress levels, May improve anxiety symptoms, May enhance testosterone in men, Supports energy and endurance, May improve sleep quality, May support thyroid function
Found in 21 products
Adaptogenic herb (Rhodiola rosea) from Arctic regions.
Benefits: Supports stress resilience, May improve mental performance under stress, May reduce fatigue, May support mood balance, May improve exercise performance
Found in 11 products
Panax ginseng (Korean/Asian ginseng) is one of the most researched adaptogens, containing ginsenosides (triterpene saponins) as primary active compounds. Over 100 ginsenosides identified, each with distinct pharmacological effects on the CNS, immune system, and endocrine function. Used for 5,000+ years in Traditional Chinese Medicine.
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Found in 9 products
Maca (Lepidium meyenii) is a Peruvian cruciferous root vegetable grown at 4,000+ meters altitude. Different color varieties (red, black, yellow) have distinct properties. It does not directly alter hormones but modulates the hypothalamic-pituitary axis. Clinically validated for libido, energy, fertility, and mood.
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Found in 3 products
Ubiquinol is the reduced (active) form of Coenzyme Q10, with 3-6x greater bioavailability than ubiquinone. It is essential for mitochondrial ATP production (electron transport chain) and is the body's most potent lipid-soluble antioxidant. Production declines with age and statin use. Heart, brain, and kidneys have highest requirements.
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Found in 3 products
Shilajit is a mineral-rich resinous substance found in Himalayan rock formations. It contains fulvic acid, dibenzo-alpha-pyrones, and 85+ minerals. Ayurvedic rasayana (rejuvenator) with clinical evidence for testosterone, mitochondrial function, and CoQ10 enhancement.
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Found in 2 products
Cordyceps (primarily C. militaris and C. sinensis) is a medicinal mushroom prized in Traditional Chinese Medicine for energy and stamina. Its active compounds include cordycepin (3-deoxyadenosine), polysaccharides, and adenosine. Research supports its use for ATP production, oxygen utilization, and exercise performance.
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Found in 2 products
Pyrroloquinoline quinone (PQQ) is a novel vitamin-like compound that stimulates mitochondrial biogenesis (the creation of NEW mitochondria) — a function unique among supplements. It also activates PGC-1alpha and Nrf2 pathways. Found in natto, parsley, and human breast milk.
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Found in 1 products
Start by addressing deficiencies: Vitamin B12 + Iron + Vitamin D — these three deficiencies are the most common causes of unexplained fatigue. Get blood work first, especially for iron.
For stress-related fatigue, combine Ashwagandha (KSM-66, 600mg) + Rhodiola (400mg). They work through different adaptogenic pathways and complement each other. Take Rhodiola in the morning (it can be mildly stimulating) and Ashwagandha any time.
For cellular energy support, add CoQ10 (Ubiquinol 100mg) + PQQ (20mg) — CoQ10 optimizes existing mitochondria while PQQ stimulates the creation of new ones.
Avoid: High-dose caffeine supplements for chronic fatigue — they mask the problem. Address root causes (nutrient deficiencies, stress, sleep) first.
Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting any supplement regimen.
